The bacterial infections are common in children as well as the adults. Both the gram-positive and the gram-negative bacteria are capable of causing diseases in human beings. The harmfulness of the illness varies from low to critical depending on the nature of the virus. Some disorders can have severe symptoms and affect the most important organs of your body. Diseases like pneumonia and bronchitis affect your lungs and may turn out to be fatal if you don’t start an early treatment. Upper torso infections can mess with your respiratory system which causes serious trouble.
Using the macrolides
Whenever you suffer from any bacterial infection, you need to take some medicines to fight against the invading germs. Now the class of medicines that work the best against the bacteria is the macrolides. The first line of treatment coming from the macrolides are for treating the community-acquired pneumonia, acute but non-specific urethritis, chlamydia, and H. pylori. If you are allergic to cephalosporin or penicillin, then the macrolides are the best option. The drugs containing macrolides that you can buy from RXShopMD are beneficial for the treatment of skin, respiratory, soft tissue, and atypical mycobacterial infections. The spectrum of the macrolides in antimicrobial activity is similar to the benzylpenicillin.
Working with particular macrolides
A very popular broad-spectrum macrolide is the Azithromycin which is an antibiotic having bacteriostatic activity. It works against various bacteria including the species of Bordetella and Chlamydia. The doctors also prescribe the drug against bacteria like Mycoplasma pneumoniae, Mycobacterium avium, Treponema pallidum, and Chlamydia species. The primary use of the medicine is for treating the genitourinary, respiratory and enteric infections. The medication gets the first preference when it comes to the treatment of sexually transmitted diseases and various enteric infections.
Mechanism of action
The reversible binding potential of the Zithromax to the ribosome of the bacteria is a unique process which stops the protein synthesis of the bacteria altogether. The oral bioavailability of the drug is between 35% to 42% in the cystic fibrosis patients as well as the healthy volunteers. The medicine has a long span of half-life as the uptake by the tissue is extensive, especially in the prostate, lung, and tonsil. After registering a single dose of 500 mg orally, the tissue concentration will increase and inhibit the pathogens from multiplying. The medicine undergoes accumulation in the phagocytes where the concentration is almost 200 times more than that in the serum.
Dosage information
The medicine is for oral uptake, but there is also the option for intravenous intake for those patients who have a problem in tolerating the oral medication. The treatment duration will vary based on the severity and indications. For the respiratory tract infections, the doctor recommends to continue the drug for several days, and the treatment will go on for months if it is a case of mycobacterial infection. The medicine has no specific interaction with the cytochrome P450 3A4. The drug is acid stable which makes it easier to consume the medicine with food.